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ailab-bio/TACK

TACK — TArgeting Chimeras Knowledge A curated, ML-ready dataset and benchmark for PROTAC degradation activity prediction Overview Proteolysis-targeting chimeras (PROTACs) are a promising drug modality that induces targeted protein degradation by hijacking the cell's native ubiquitin–proteasome system. However, rational PROTAC design remains challenging due to the complex interplay between molecular structure, target proteins (POIs), E3 ligases, and cellular… See the full description on the dataset page: https://huggingface.co/datasets/ailab-bio/TACK.

Author / organizationailab-bio
License (as declared)mit
Downloads173 (as reported by Hugging Face)
Likes2
Created9 December 2025
Last updated at source20 May 2026
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