LiteFold/CycPepMPDB

CycPepMPDB CycPeptMPDB (Cyclic Peptide Membrane Permeability Database) is the standard public dataset of experimentally measured membrane permeability for cyclic peptides, released in 2023 by Akiyama and colleagues at Tokyo Institute of Technology. It exists because cyclic peptides have become a serious modality for hitting "undruggable" intracellular targets like protein-protein interfaces, but their typically poor passive permeability is the bottleneck of the field, and until… See the full description on the dataset page: https://huggingface.co/datasets/LiteFold/CycPepMPDB.

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